Thermo Fisher Scientific CIDE-3 Polyclonal Antibody
Human CIDE-3 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot에 적합. 합성 펩타이드(aa 10-25)를 면역원으로 사용. Protein A로 정제된 액상 형태이며 PBS(pH 7.4)에 보존제 없이 제공. -20°C 보관, 반복 동결/해동 피함.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 10–25 (LLYPKSLSRHVSVRTS) of human CIDE-3 conjugated to KLH at the C-terminus |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
DNA fragmentation is one of the critical steps in apoptosis, which is induced by DNA fragmentation factor (DFF). DFF is composed of two subunits, a 40 kDa caspase-activated nuclease (DFF40) and a 45 kDa inhibitor (DFF45).
Recently, a novel family of cell-death-inducing DFF45-like effectors (CIDEs) has been identified. Human CIDE-3 is a novel member of CIDEs.
Two transcripts, CIDE-3 and CIDE-3α, are present in HepG2 and A375 cells.
Consistent with its chromosome localization at 3p25, a region associated with high frequency loss of heterozygosity in many tumors, CIDE-3 may play an important role in prevention of tumorigenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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