Thermo Fisher Scientific HDAC6 Monoclonal Antibody (3A6)
HDAC6 단백질을 표적으로 하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 3A6). Western blot, ICC/IF, ELISA 등 다양한 응용에 사용 가능. 인간 반응성, 액상 형태, 보존제 무첨가, -20°C 보관.
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Thermo Fisher Scientific HDAC6 Monoclonal Antibody (3A6)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A6 |
| Immunogen | HDAC6 (AAH13737, 1 a.a. ~1063 a.a) full-length recombinant protein with GST tag (MW of GST tag = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of HDAC6 protein:
METTQYMNEG ELRVLADTYD SVYLHPNSYS CACLASGSVL RLVDAVLGAE IRNGMAIIRP PGHHAQHSLM DGYCMFNHVA VAARYAQQKH RIRRVLIVDW DVHHGQGTQF TFDQDPSVLY FSIHRYEQGR FWPHLKASNW STTGFGQGQG YTINVPWNQV GMRDADYIAA FLHVLLPVAL EFQPQLVLVA AGFDALQGDP KGEMAATPAG FAQLTHLLMG LAGGKLILSL EGGYNLRALA EGVSASLHTL LGDPCPMLES PGAPCRSAQA SVSCALEALE PFWEVLVRST ETVERDNMEE DNVEESEEEG PWEPPVLPIL TWPVLQSRTG LVYDQNMMNH CNLWDSHHPE VPQRILRIMC RLEELGLAGR CLTLTPRPAT EAELLTCHSA EYVGHLRATE KMKTRELHRE SSNFDSIYIC PSTFACAQLA TGAACRLVEA VLSGEVLNGA AVVRPPGHHA EQDAACGFCF FNSVAVAARH AQTISGHALR ILIVDWDVHH GNGTQHMFED DPSVLYVSLH RYDHGTFFPM GDEGASSQIG RAAGTGFTVN VAWNGPRMGD ADYLAAWHRL VLPIAYEFNP ELVLVSAGFD AARGDPLGGC QVSPEGYAHL THLLMGLASG RIILILEGGY NLTSISESMA ACTRSLLGDP PPLLTLPRPP LSGALASITE TIQVHRRYWR SLRVMKVEDR EGPSSSKLVT KKAPQPAKPR LAERMTTREK KVLEAGMGKV TSASFGEEST PGQTNSETAV VALTQDQPSE AATGGATLAQ TISEAAIGGA MLGQTTSEEA VGGATPDQTT SEETVGGAIL DQTTSEDAVG GATLGQTTSE EAVGGATLAQ TTSEAAMEGA TLDQTTSEEA PGGTELIQTP LASSTDHQTP PTSPVQGTTP QISPSTLIGS LRTLELGSES QGASESQAPG EENLLGEAAG GQDMADSMLM QGSRGLTDQA IFYAVTPLPW CPHLVAVCPI PAAGLDVTQP CGDCGTIQEN WVCLSCYQVY CGRYINGHML QHHGNSGHPL VLSYIDLSAW CYYCQAYVHH QALLDVKNIA HQNKFGEDMP HPH
Target Information
HDAC6는 히스톤 단백질(H2A, H2B, H3, H4)의 N-말단 라이신 잔기의 탈아세틸화를 담당합니다. 이는 전사 억제의 후성유전학적 신호로 작용하며, 세포 주기 조절 및 발달 과정에 중요한 역할을 합니다. 또한, HDAC6는 tubulin 탈아세틸화를 통해 미세소관 의존성 세포 운동성 조절에 중심적인 역할을 합니다.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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