Thermo Fisher Scientific HDAC6 Monoclonal Antibody (3A6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

ELISA (ELISA)

0.3 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

3A6

Immunogen

HDAC6 (AAH13737, 1 a.a. approximately 1063 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HDAC6,uniProtId:Q9UBN7-1,ncbiNodeId:9606,antigenRange:1-1215,antigenLength:1215,antigenImageFileName:H00010013-M13_HDAC6_Q9UBN7-1_House_mouse.svg,antigenImageFileNamePDP:H00010013-M13_HDAC6_Q9UBN7-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: METTQYMNEG ELRVLADTYD SVYLHPNSYS CACLASGSVL RLVDAVLGAE IRNGMAIIRP PGHHAQHSLM DGYCMFNHVA VAARYAQQKH RIRRVLIVDW DVHHGQGTQF TFDQDPSVLY FSIHRYEQGR FWPHLKASNW STTGFGQGQG YTINVPWNQV GMRDADYIAA FLHVLLPVAL EFQPQLVLVA AGFDALQGDP KGEMAATPAG FAQLTHLLMG LAGGKLILSL EGGYNLRALA EGVSASLHTL LGDPCPMLES PGAPCRSAQA SVSCALEALE PFWEVLVRST ETVERDNMEE DNVEESEEEG PWEPPVLPIL TWPVLQSRTG LVYDQNMMNH CNLWDSHHPE VPQRILRIMC RLEELGLAGR CLTLTPRPAT EAELLTCHSA EYVGHLRATE KMKTRELHRE SSNFDSIYIC PSTFACAQLA TGAACRLVEA VLSGEVLNGA AVVRPPGHHA EQDAACGFCF FNSVAVAARH AQTISGHALR ILIVDWDVHH GNGTQHMFED DPSVLYVSLH RYDHGTFFPM GDEGASSQIG RAAGTGFTVN VAWNGPRMGD ADYLAAWHRL VLPIAYEFNP ELVLVSAGFD AARGDPLGGC QVSPEGYAHL THLLMGLASG RIILILEGGY NLTSISESMA ACTRSLLGDP PPLLTLPRPP LSGALASITE TIQVHRRYWR SLRVMKVEDR EGPSSSKLVT KKAPQPAKPR LAERMTTREK KVLEAGMGKV TSASFGEEST PGQTNSETAV VALTQDQPSE AATGGATLAQ TISEAAIGGA MLGQTTSEEA VGGATPDQTT SEETVGGAIL DQTTSEDAVG GATLGQTTSE EAVGGATLAQ TTSEAAMEGA TLDQTTSEEA PGGTELIQTP LASSTDHQTP PTSPVQGTTP QISPSTLIGS LRTLELGSES QGASESQAPG EENLLGEAAG GQDMADSMLM QGSRGLTDQA IFYAVTPLPW CPHLVAVCPI PAAGLDVTQP CGDCGTIQEN WVCLSCYQVY CGRYINGHML QHHGNSGHPL VLSYIDLSAW CYYCQAYVHH QALLDVKNIA HQNKFGEDMP HPH

Target Information

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.