Thermo Fisher Scientific MICA Polyclonal Antibody
Thermo Fisher Scientific의 MICA Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하는 Rabbit IgG 항체입니다. Western blot 및 ELISA에 적합하며, 세포막 및 세포질 내 MICA 단백질 검출에 사용됩니다. 고순도 Affinity Chromatography 정제 제품으로 안정적 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 24–307 of human MICA (NP_0002381) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.21 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805624 |
Product Specific Information
Immunogen sequence:
EPHSLRYNLT VLSWDGSVQS GFLTEVHLDG QPFLRCDRQK CRAKPQGQWA EDVLGNKTWD RETRDLTGNG KDLRMTLAHI KDQKEGLHSL QEIRVCEIHE DNSTRSSQHF YYDGELFLSQ NLETKEWTMP QSSRAQTLAM NVRNFLKEDA MKTKTHYHAM HADCLQELRR YLKSGVVLRR TVPPMVNVTR SEASEGNITV TCRASGFYPW NITLSWRQDG VSLSHDTQQW GDVLPDGNGT YQTWVATRIC QGEEQRFTCY MEHSGNHSTH PVPSGKVLVL QSHW
Positive Samples:
MCF7, SW480, NCI-H460, HepG2, HeLa, Mouse kidney, Mouse ovary, Rat kidney
Cellular Location:
Cell membrane, Cytoplasm, Single-pass type I membrane protein
Target Information
Major histocompatibility complex (MHC) class I proteins mediate recognition of intracellular antigens by cytotoxic T cells. The MHC class I chain-related (MIC) proteins, including MICA, are recognized by NKG2D receptors on NK and T cells, promoting anti-tumor activity. MICA is widely expressed on various tumors and most normal tissues except the nervous system, suggesting its role in immune system-mediated anti-tumor responses.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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