Thermo Fisher Scientific Gephyrin Polyclonal Antibody
Thermo Fisher Scientific의 Gephyrin Polyclonal Antibody는 인간 Gephyrin 단백질을 인식하는 토끼 다클론 항체입니다. Western blot과 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 완충액 형태로 제공됩니다. 연구용 전용 제품입니다.
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- PA551827
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Gephyrin. Recombinant protein control fragment (Product #RP-89067) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641959 |
Product Specific Information
Immunogen sequence:
ATIQEHGYPT INLGIVGDNP DDLLNALNEG ISRADVIITS GGVSMGEKDY LKQVLDIDLH AQIHFGRVFM KPGLPTTFAT LDIDGVRKII FALPGNPVSA VVTCNLFVVP ALRKMQGILD PRPTIIKARL SCDVKLDPRP EY
Antigen sequence identity:
Mouse – 100%
Rat – 100%
Target Information
Gephyrin is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In non-neuronal tissues, it is also required for molybdenum cofactor biosynthesis. Mutations in this gene are associated with neurological conditions such as hyperplexia and molybdenum cofactor deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been described, but not all full-length sequences are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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