Thermo Fisher Scientific Human EFHD2 Synthetic Peptide
인간 EFHD2 아미노 말단 16개 아미노산 서열 기반 합성 펩타이드. 항체 PA5-20919의 블로킹 펩타이드로 사용 가능. B세포 수용체 신호전달 연구에 활용. 액상 형태, 200 µg/mL 농도, PBS 버퍼에 0.1% BSA 포함.
- 카탈로그번호
- PEP1033
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the amino terminus of human EFHD2.
PEP-1033 can be used as a blocking peptide with polyclonal antibody PA5-20919.
Target Information
EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold required for the Syk-, SLP-65-, and PLC-gamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance and acts as a negative regulator of the canonical NF-kappa-B-activating branch.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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