Thermo Fisher Scientific GABPA Monoclonal Antibody (8C1B10)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:200-1:1,000

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

8C1B10

Immunogen

Purified recombinant fragment of human GABPA (aa120-190) expressed in E. Coli. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GABPA,uniProtId:Q06546-1,ncbiNodeId:9606,antigenRange:120-190,antigenLength:454,antigenImageFileName:MA5-15419_GABPA_Q06546-1_House_mouse.svg,antigenImageFileNamePDP:MA5-15419_GABPA_Q06546-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.03% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_10977231

Product Specific Information

MA5-15419 targets GABPA in indirect ELISA, IF ICC and WB applications and shows reactivity with Human and mouse samples.

The MA5-15419 immunogen is purified recombinant fragment of human GABPA (aa120-190) expressed in E. Coli.

.

MA5-15419 detects GABPA which has a predicted molecular weight of approximately 51kDa.

Target Information

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.