Thermo Fisher Scientific ANKLE2 Polyclonal Antibody
Human ANKLE2 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot에 최적화됨. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 용액 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 시약.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ANKLE2. Recombinant protein control fragment (Product # RP-102178) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2637950 |
Product Specific Information
Immunogen sequence:
SETVNKERAN SYKNPRTQDL TAKLRKAVEK GEEDTFSDLI WSNPRYLIGS GDNPTIVQEG CRYNVMHVAA KENQASICQL TLDVLENPDF MRLMYPDDDE AMLQKRIRYV VDLYLNTPDK MGYDTPLHFA CKFGNADVVN VLSSH
- Highest antigen sequence identity to orthologs:
- Mouse: 91%
- Rat: 90%
Target Information
This gene encodes a human guanine nucleotide exchange factor that transduces signals from CRK by binding the SH3 domain of CRK and activating several members of the Ras family of GTPases.
This signaling cascade may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation.
Several alternatively spliced transcript variants have been described, though full-length nature of some variants remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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