Thermo Fisher Scientific Lamin B Receptor Polyclonal Antibody
Thermo Fisher Scientific의 Lamin B Receptor Polyclonal Antibody는 인간 Lamin B 수용체를 인식하는 rabbit IgG 기반 항체입니다. Western blot 및 ICC/IF에 적합하며, 고순도의 항원 친화 크로마토그래피로 정제되었습니다. 장기 보관 시 -20°C에서 안정적입니다.
- 카탈로그번호
- PA566473
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- View 2 publications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- View publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Lamin B Receptor. Recombinant protein control fragment (Product #RP-105228) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663311 |
Product Specific Information
Immunogen sequence:
EARREVEVKLT PLILKPFGNS ISRYNGEPEH IERNDAPHKN TQEKFNLSQE SSYIATQYSL RPRREEVKLK EIDSKEEKYV AKELAVRTF
- Highest antigen sequence identity to the following orthologs:
- Mouse: 62%
- Rat: 38%
Target Information
The protein encoded by this gene belongs to the ERG4/ERG24 family. It is localized in the nuclear envelope inner membrane and anchors the lamina and heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene have been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus, and two transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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