Thermo Fisher Scientific PPP2R3A Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.04–0.4 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:200–1:500

Product Specifications

Product Specific Information

Immunogen sequence:
EQRDPFAVQK DVENDGPEPS DWDRFAAEEY ETLVAEESAQ AQFQEGFEDY ETDEPASPSE FGNKSNKILS ASLPEKCGKL QSVDEE

Highest antigen sequence identity to the following orthologs:

• Mouse: 85%
• Rat: 85%

Target Information

Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B/PR61, and B/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holoenzyme. The product of this gene belongs to the Bfamily, specifically the alpha subfamily of regulatory subunit B. Alternative splicing results in multiple transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.