Thermo Fisher Scientific EIF3L Polyclonal Antibody
Rabbit에서 생산된 EIF3L 단백항체로 Western blot과 Immunoprecipitation에 적합. 인간 EIF3L 단백질 1–50번 영역을 면역원으로 사용. 액상형 비결합 항체로 1 mg/mL 농도, 4°C 보관. 다양한 종(X. tropicalis, Chicken 등)과 교차 반응 예상.
- 카탈로그번호
- A304753Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific EIF3L Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 to 50 of human Eukaryotic Translation Initiation Factor 3 Subunit L |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with X. tropicalis, Chicken, Bovine, and Chimpanzee
Target Information
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, required for several steps in the initiation of protein synthesis.
The eIF-3 complex associates with the 40S ribosome and facilitates recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi, and eIF-5 to form the 43S pre-initiation complex (43S PIC).
It stimulates mRNA recruitment and scanning for AUG recognition, assists in disassembly and recycling of post-termination ribosomal complexes, and prevents premature joining of 40S and 60S subunits prior to initiation.
The complex specifically targets and initiates translation of mRNAs involved in cell proliferation, differentiation, and apoptosis, using different RNA stem-loop binding modes for translational activation or repression.
[UniProt]
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지: A304-753A-M_eIF3l_Q9Y262-1_Rabbit.svg)
(이미지: A304-753A-M_eIF3l_Q9Y262-1_Rabbit_PDP.jpeg)
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