Thermo Fisher Scientific USP37 Polyclonal Antibody
Thermo Fisher Scientific의 USP37 폴리클로날 항체는 인간 USP37 단백질을 표적으로 하며 Western blot에 최적화된 고품질 연구용 항체입니다. 항원 친화 크로마토그래피로 정제되었으며 1 mg/mL 농도로 제공됩니다. 인간에 반응하며, 마우스·개·소에서도 예측 반응성을 보입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 617–892 of Human USP37 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548740 |
Product Specific Information
- Recommended positive controls: 293T
- Predicted reactivity: Mouse (87%), Dog (91%), Bovine (94%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of Lys-11-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of Lys-48-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, preventing degradation of cyclin-A (CCNA1 and CCNA2). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1. [UniProt]
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-31266_USP37_Q86T82-1_Rabbit.svg, PA5-31266_USP37_Q86T82-1_Rabbit_PDP.jpeg)
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