Thermo Fisher Scientific KHDC1 Polyclonal Antibody
Human KHDC1 단백질을 인식하는 Rabbit Polyclonal 항체로, ICC/IF 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 glycerol buffer에 보관됩니다. 연구용으로만 사용 가능하며 장기 보관 시 -20°C에서 보관 권장.
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KHDC1. Recombinant protein control fragment (Product #RP-94834). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642987 |
Product Specific Information
- Immunogen sequence:
RERNSRSGKT RCRSKRSEQS MDMGTSALSK KPWWTLPQNF HAPMVFHMEE DQEELIFGHG D - Highest antigen sequence identity to orthologs:
Mouse – 33%, Rat – 38%
Target Information
KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins involved in RNA metabolism, including transcription, splicing, transport, translation, and stability.
KHDC1 is highly expressed in oocytes and interacts with CPEB1, a key translational regulator controlling polyA tail length of mRNAs.
KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway. The C-terminal trans-membrane motif (TMM) is critical for its activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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