Thermo Fisher Scientific SNAI2 Monoclonal Antibody (OTI1A6), TrueMAB
SNAI2 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, IHC, Flow cytometry에 적합합니다. 인간 시료 반응성이 있으며, 액상 형태로 1 mg/mL 농도 제공. PBS/BSA/glycerol buffer에 보관하며 -20°C에서 안정적입니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A6 |
| Immunogen | Full length human recombinant protein of human SNAI2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Slug (SNAI2) is a member of the Snail family of C2H2-type zinc finger transcription factors. It plays a key role in epithelial-mesenchymal transitions and neural tube formation during vertebrate embryogenesis. Slug transcription is induced by growth factors such as FGF, BMP, and TGF-beta, and it represses transcription of genes like E-cadherin and Claudin-1 by binding to E-box regions. Its expression in breast, esophageal, and colorectal carcinomas correlates with poor prognosis. Additionally, Slug protects hematopoietic progenitor cells from radiation-induced apoptosis by repressing p53-mediated transcription of Puma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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