Thermo Fisher Scientific ATP1A1 Polyclonal Antibody
Rabbit polyclonal antibody against ATP1A1 detecting human, mouse, and rat proteins. Validated for WB and IHC(P) applications. High purity (>95%) and antigen affinity purified. Supplied in PBS with glycerol for stability. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human Na⁺/K⁺-ATPase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803931 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
The ATP1A1 gene encodes a protein belonging to the family of P-type cation transport ATPases, specifically the Na⁺/K⁺-ATPases. This integral membrane protein maintains electrochemical gradients of sodium and potassium ions across the plasma membrane, essential for osmoregulation, sodium-coupled transport of various molecules, and electrical excitability in nerve and muscle cells.
Na⁺/K⁺-ATPase consists of two subunits: a large catalytic alpha subunit and a smaller glycoprotein beta subunit. The alpha 1 subunit is encoded by ATP1A1, with multiple transcript variants producing different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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