Thermo Fisher Scientific CLDN6 Monoclonal Antibody (OTI4B5), TrueMAB
인간 CLDN6 단백질을 타깃으로 하는 Mouse IgG1 단클론 항체. Western blot과 Immunocytochemistry에 최적화됨. Affinity chromatography로 정제된 액상 형태로 제공. 세포 간 밀착연구 및 HCV 관련 연구용에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B5 |
| Immunogen | Full length human recombinant protein of human CLDN6 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet.
The CLDN6 gene encodes a component of tight junction strands, belonging to the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus (HCV). Gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member, CLDN9, on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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