Thermo Fisher Scientific KV2.2 (KCNB2) Polyclonal Antibody
Thermo Fisher Scientific의 KV2.2 (KCNB2) Rabbit Polyclonal Antibody는 인간 KCNB2 단백질을 인식하며 Western blot에 적합합니다. KLH 결합 합성 펩타이드로 면역화된 항체로, 고순도 Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between amino acids 138–166 from the N-terminal region of human KCNB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2634672 |
Product Specific Information
Predicted to react with bovine, mouse, and rabbit based on sequence homology.
Target Information
KCNB2 (Kv2.2) encodes a voltage-gated potassium channel that regulates neuronal membrane excitability. Differences in K+ channel expression and density contribute to variations in action potential waveforms and firing patterns among neuronal cell types. Kv2.1 and KCNB2 form distinct channel populations responsible for delayed rectifier-type currents (IK) in superior cervical ganglion cells. KCNB2 mediates voltage-dependent potassium ion permeability, opening or closing in response to membrane potential changes. Associated diseases include Brugada Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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