Thermo Fisher Scientific MnSOD Polyclonal Antibody

Applications

• Western Blot (WB)
  Tested Dilution: 1:1,000–1:4,000

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Human, Guinea pig, Pig, Monkey, and Chimpanzee

Target Information

Superoxide dismutase (SOD) is an antioxidant enzyme that protects cells against reactive oxygen species (ROS). It catalyzes the dismutation of superoxide radicals (O₂⁻) to hydrogen peroxide (H₂O₂), which is further converted to water and oxygen by glutathione peroxidase and catalase.
There are several SOD isoforms:

• SOD1 (Cu,Zn-SOD): Cytosolic enzyme found in all eukaryotes; homodimeric 32 kDa structure.
• SOD2 (Mn-SOD): Mitochondrial enzyme; tetrameric 80 kDa structure located in the mitochondrial matrix.
• SOD3 (EC-SOD): Extracellular enzyme; heparin-binding multimer expressed in lungs, vessel walls, and airways.
• SOD4 (CCS): Copper chaperone that delivers Cu to SOD1 for activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

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