Thermo Fisher Scientific CD193 (CCR3) Monoclonal Antibody (5E8), APC
CD193(CCR3) 단백질의 세포 표면 발현을 검출하기 위한 APC 형광 표지 단클론 항체. 인간 시료에 반응하며, Flow Cytometry에 최적화. 4°C 보관, 동결 금지. 연구용으로만 사용.
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Thermo Fisher Scientific CD193 (CCR3) Monoclonal Antibody (5E8), APC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 10 µL / 10^6 cells
References: Publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5E8 |
| Immunogen | Human CD193 transfectants |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898647 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope of CD193 (chemokine receptor 3), an approximately 41 kDa protein expressed primarily in eosinophils and basophils.
Target Information
CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta. CCR3 transduces signals by increasing intracellular calcium ion levels and serves as an alternative co-receptor with CD4 for HIV-1 infection. Chemokines play key roles in inflammation and in recruiting effector immune cells to infection sites. These receptors are divided into two major groups, CXCR and CCR, based on chemokine classes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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