Thermo Fisher Scientific ARL2BP Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ARL2BP. Recombinant protein control fragment (Product #RP-100103). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ARL2BP,uniProtId:Q9Y2Y0-1,ncbiNodeId:9606,antigenRange:85-160,antigenLength:163,antigenImageFileName:PA5-61734_ARL2BP_Q9Y2Y0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61734_ARL2BP_Q9Y2Y0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638197

Product Specific Information

Immunogen sequence: IPEFNMAAFT TTLQHHKDEV AGDIFDMLLT FTDFLAFKEM FLDYRAEKEG RGLDLSSGLV VTSLCKSSSL PASQNN

Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

Target Information

ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2. GTP with high affinity but does not interact with ARL2. GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2. GTP but lack of ARL2 GTPase-activating protein activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.