Thermo Fisher Scientific LILRB3 Polyclonal Antibody, FITC
FITC로 표지된 Thermo Fisher Scientific의 LILRB3 폴리클로날 항체로, 마우스 시료에 반응합니다. WB, ELISA, IP 등 다양한 응용에 적합하며, 친화 크로마토그래피로 정제되었습니다. 498/517 nm 형광 특성을 가지며, -20°C에서 암소 보관이 필요합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within amino acid region 800–841 on mouse LILRB3 protein |
| Conjugate | FITC (Fluorescein Isothiocyanate) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, located in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors, which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs).
The receptor is expressed on immune cells, binds to MHC class I molecules on antigen-presenting cells, and transduces a negative signal that inhibits immune stimulation. It helps control inflammatory responses and cytotoxicity, focusing the immune response and limiting autoreactivity. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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