
Thermo Fisher Scientific Ralpancizumab Humanized Recombinant Human Monoclonal Antibody
Ralpancizumab 인간화 재조합 단일클론 항체로, PCSK9을 타겟으로 하는 연구용 시약입니다. ELISA 등 다양한 면역분석에 사용 가능하며, 고순도 Protein A 정제 및 낮은 엔도톡신 수준을 특징으로 합니다. 냉동(-20°C 이하) 보관 권장.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG2, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Human PCSK9 / NARC1 / PC9 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.73 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.5 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911161 |
Product Specific Information
- Endotoxin level: < 0.01 EU/µg by LAL method
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for one week.
- Store at -20 to -80°C for up to twelve months from the date of receipt.
Target Information
Ralpancizumab is a biosimilar that targets PCSK9, a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family.
PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum.
It plays a key role in cholesterol homeostasis and may contribute to the differentiation of cortical neurons.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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