Thermo Fisher Scientific WDR20 Polyclonal Antibody
WDR20 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC, IP 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, 인간 및 마우스 시료에 반응. 4°C 보관, 연구용 전용.
- 카탈로그번호
- A301657A
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 450 and 500 of Human WD repeat domain 20 (WDR20, UniProt ID: Q8TBZ3-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
CUL-2 is a member of the human cullin gene family (CUL-1, -2, -3, -4a, -4b, and -5), homologous to the S. cerevisiae cdc53 gene.
CUL-1 forms a complex with human p19skp1 and F-box protein p45skp2, functioning as a ubiquitin ligase controlling proteolysis of G1 cell cycle regulatory proteins.
In contrast, CUL-2 does not associate with p19skp1 and p45skp2 but forms a complex with the inactive transcriptional elongation complex SIII (Elongin C, Elongin B, and VHL).
The function of this association remains unknown.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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