
Thermo Fisher Scientific RORA Polyclonal Antibody
RORA 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, Flow cytometry, ChIP 등 다양한 응용에 사용 가능. 인간 및 생쥐 시료에 반응하며, Protein A 및 항원 친화 크로마토그래피로 정제. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | - |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | - | 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | - | 1 publication |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 | - |
| Flow Cytometry (Flow) | 1:25 | 1 publication |
| ChIP assay (ChIP) | - | 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 193–222 of human RORA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.0 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2285213 |
Product Specific Information
This antibody is predicted to react with mouse based on sequence homology.
Target Information
RORA (Retinoic acid receptor-related orphan receptor alpha) is a nuclear receptor belonging to the NR1 subfamily of nuclear hormone receptors. It binds as a monomer or homodimer to retinoic acid response elements to regulate gene expression and control cell function. RORA interacts with NM23-2, NM23-1, CDK7, NCOA3, and NCOA6 coactivators, and is expressed in mesenchymal stem cells derived from bone marrow, influencing bone matrix modulation. It is widely expressed in most tissues. Chromosomal aberrations involving RORA may contribute to acute promyelocytic leukemia (APL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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