Thermo Fisher Scientific CACNG6 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CACNG6 protein. Validated for WB and IHC applications. Recognizes conserved regions in mouse and rat. Supplied lyophilized, reconstitute in sterile water. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the internal region of human CACNG6 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in mouse and shares 95% identity with rat sequence.
- Specificity: CACNG6.
Target Information
Voltage-dependent calcium channels are composed of five subunits. The CACNG6 gene encodes one of the gamma subunits, an integral membrane protein thought to stabilize the calcium channel in an inactive (closed) state. This gene belongs to a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members functioning as transmembrane AMPA receptor regulatory proteins (TARPs).
Alternative splicing results in multiple transcript variants. Variants in this gene have been associated with aspirin-intolerant asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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