Thermo Fisher Scientific Human CRMP1 Synthetic Peptide
인간 CRMP1 단백질의 N말단 18개 아미노산 서열에 해당하는 합성 펩타이드로, 항체 PA5-20677의 블로킹 펩타이드로 사용 가능. 신경세포 분화 및 축삭 성장 연구용. PBS 완충액에 0.1% BSA 포함, -20°C 보관.
- 카탈로그번호
- PEP0795
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the amino terminus of human CRMP-1.
PEP-0795 can be used as a blocking peptide with polyclonal antibody PA5-20677.
Target Information
Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity.
CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain; later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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