Thermo Fisher Scientific SEMA3F Polyclonal Antibody
Human SEMA3F 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200~1:500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 버퍼에 보관. 연구용으로만 사용.
- 카탈로그번호
- PA557111
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SEMA3F. Recombinant protein control fragment (Product #RP-96247) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647107 |
Product Specific Information
Immunogen sequence:
TPPYQELAQL LAQPEVGLIH QYCQGYWRHV PPSPREAPGA PRSPEPQDQK KPRNRRHHPP DT
Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 94%
Target Information
The semaphorins are a family of proteins involved in signaling. All family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues (Kolodkin et al., 1993 [PubMed 8269517]).
Sequence comparisons have grouped the secreted semaphorins into three general classes, all of which also have an immunoglobulin domain. The semaphorin III family, including human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus.
Chicken collapsin contributes to axon pathfinding during development by inhibiting growth cone extension (Luo et al., 1993 [PubMed 8402908]) through interaction with CRMP62 (Goshima et al., 1995 [PubMed 7637782]), a homolog of the UNC33 gene product (MIM 601168).
SEMA3F is a secreted member of the semaphorin III family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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