Thermo Fisher Scientific STING1/TMEM173 Recombinant Rabbit Monoclonal Antibody (STING1/8129R)
STING1/TMEM173 단백질을 인식하는 재조합 토끼 단클론 항체로, 면역조직화학(IHC) 분석에 적합합니다. 인간 시료 반응성이 있으며, Protein A/G로 정제된 고순도 항체입니다. PBS(pH 7.4)에 보존되어 있으며 방부제는 포함되지 않습니다.
- 카탈로그번호
- 8129R-P1ABX
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | STING1/8129R |
| Immunogen | Recombinant fragment (aa190–290) of human TMEM173 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
STING (Stimulator of Interferon Genes) is a 379-amino-acid signaling protein that plays a key role in innate immune signaling. It activates NF-κB and IRF3 transcription pathways to induce type I interferon (IFN-α, IFN-β) expression, establishing an antiviral state. STING may also function as a translocon influencing interferon induction and mediating apoptotic signaling via MHC-II association. It is primarily localized to the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed across most tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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