Thermo Fisher Scientific FIP1L1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human FIP1L1. Recombinant protein control fragment (Product #RP-96672). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FIP1L1,uniProtId:Q6UN15-1,ncbiNodeId:9606,antigenRange:287-367,antigenLength:594,antigenImageFileName:PA5-57963_FIP1L1_Q6UN15-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57963_FIP1L1_Q6UN15-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641643

Product Specific Information

Immunogen sequence: KANSSVGKWQ DRYGRAESPD LRRLPGAIDV IGQTITISRV EGRRRANENS NIQVLSERSA TEVDNNFSKP PPFFPPGAPP T

Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Target Information

FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3`-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. It binds to U-rich RNA sequence elements surrounding the poly(A) site. FIP1L1 may act to tether poly(A) polymerase to the CPSF complex.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.