Thermo Fisher Scientific beta-2 Adrenergic Receptor Polyclonal Antibody
Rabbit polyclonal antibody against human beta-2 adrenergic receptor. Validated for Western blot (1:1,000). Purified via Protein A and antigen affinity chromatography. Supplied in PBS with 0.09% sodium azide. Suitable for research use only.
- 카탈로그번호
- PA514119
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 364–393 of human ADRB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2225413 |
Target Information
Adrenergic receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor (GPCR) superfamily that bind the endogenous catecholamines epinephrine and norepinephrine. Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family.
Nine receptor subtypes have been identified, including:
- Three alpha-1 AR subtypes (1A/D, 1B, 1C)
- Three alpha-2 AR subtypes (2A, 2B, 2C)
- Three beta AR subtypes (1, 2, 3)
ARs are implicated in various disease states, including hypertension, cardiac dysfunction (heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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