Thermo Fisher Scientific NOS1AP Polyclonal Antibody
Rabbit polyclonal antibody against human NOS1AP, suitable for WB and Flow Cytometry. Predicted cross-reactivity with mouse and rat. Purified by Protein A and antigen affinity chromatography. Supplied in PBS with sodium azide, ideal for research use only.
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- PA523774
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between amino acids 437–466 from the central region of human NOS1AP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541274 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
The NOS1AP gene encodes a cytosolic protein that binds to neuronal nitric oxide synthase (nNOS). It contains a C-terminal PDZ-binding domain mediating interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small G protein Dexras1. Studies indicate that NOS1AP acts as an adapter linking nNOS to specific targets such as Dexras1 and synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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