Thermo Fisher Scientific GGA1 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

GGA1 (NP_001001560.1, 1 a.a. approximately 552 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GGA1,uniProtId:Q9UJY5-1,ncbiNodeId:9606,antigenRange:1-639,antigenLength:639,antigenImageFileName:H00026088-D01P_GGA1_Q9UJY5-1_Rabbit.svg,antigenImageFileNamePDP:H00026088-D01P_GGA1_Q9UJY5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MEPAMEPETL EARINRATNP LNKELDWASI NGFCEQLNED FEGPPLATRL LAHKIQSPQE WEAIQALTVL ETCMKSCGKR FHDEVGKFRF LNELIKVVSP KYLGSRTSEK VKNKILELLY SWTVGLPEEV KIAEAYQMLK KQGIVKSDPK LPDDTTFPLP PPRPKNVIFE DEEKSKMLAR LLKSSHPEDL RAANKLIKEM VQEDQKRMEK ISKRVNAIEE VNNNVKLLTE MVMSHSQGGA AAGSSEDLMK ELYQRCERMR PTLFRLASDT EDNDEALGLS DPTPPSGPSL DGTGWNSFQS SDATEPPAPA LAQAPSMESR PPAQTSLPAS SGLDDLDLLG KTLLQQSLPP ESQQVRWEKQ QPTPRLTLRD LQNKSSSCSS PSSSATSLLH TVSPEPPRPP QQPVPTELSL ASITVPLESI KPSNILPVTV YDQHGFRILF HFARDPLPGR SDVLVVVVSM LSTAPQPIRN IVFQSAVPKV MKVKLQPPSG TELPAFNPIV HPSAITQVLL LANPQKEKVR LRYKLTFTMG DQTYNEMGDV DQFPPPETWG SL

Target Information

This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.