Thermo Fisher Scientific LGR7 Polyclonal Antibody
Rabbit polyclonal antibody targeting human LGR7 for IHC (Paraffin) applications. Detects G protein-coupled receptor LGR7 with high specificity. Provided in liquid form at 1 mg/mL concentration. Suitable for research use only; not for diagnostic procedu...
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 10–13 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from N-terminal extracellular domain of human LGR7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2184725 |
Product Specific Information
PA1-20464 detects G Protein-Coupled Receptor LGR7 in human samples.
Target Information
LGR7 is a low-density lipoprotein receptor of 757 amino acids belonging to the G-protein coupled receptor 1 family with rhodopsin-like receptor activity.
It has seven transmembrane regions, a cysteine-rich motif, 10 LRR domains, and 5 N-glycosylation sites in the N terminus.
Research reports show that it acts as a receptor for relaxins (RLN1 and RLN2), stimulating adenylate cyclase activation, substrate adhesion, and chemo-migratory capacity of mononuclear leukocytes.
LGR7 is critical for mediating these biological responses via RNA interference lentiviral short hairpin constructs.
It is widely expressed in 86% of 15 primary EC tissue samples including brain, kidney, testis, and endometrium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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