Thermo Fisher Scientific SPDL1 Polyclonal Antibody
Human SPDL1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: Not specified
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
- View references
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SPDL1. Recombinant protein control fragment (Product #RP-100098) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647825 |
Product Specific Information
Immunogen sequence:
YEPEETVEVP VLKKRREVLP VDITTAKDAC VNNSALGGEV YRLPPQKEET QSCPNSLEDN NLQLEKSVSI HTPVVSLSPH KNLPVDMQLK KEKKCVKLIG VPADA
Highest antigen sequence identity to orthologs:
- Mouse: 55%
- Rat: 50%
Target Information
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (basal and suprabasal layers) and mainly found in stratified squamous epithelium. It is moderately repressed by retinoic acid. The antigen localizes to basal keratinocytes and lower levels in suprabasal layers, concentrating in areas of cell-to-cell contact. This localization and down-regulation in cultured keratinocytes suggest a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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