Thermo Fisher Scientific C11orf84 Polyclonal Antibody
C11orf84 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot 및 Immunocytochemistry에 사용 가능하며, Human 시료에 반응합니다. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 안정성을 제공합니다.
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Applications
Western Blot (WB)
- Tested Dilution: Not specified
- Publications: View 1 publication
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- Publications: None listed
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human C11orf84 (Recombinant protein control fragment, Product #RP-104895) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664617 |
Product Specific Information
Immunogen sequence:
PGNKKPRGQRW KEPPGEEPVR KKRGRPMTKN LDPDPEPPSP DSPTETFAAP AEVRHFTDGS FPAGFVLQLF SHTQLRGPDS KDSPKDREVA EG
Highest antigen sequence identity to orthologs:
- Mouse: 81%
- Rat: 80%
Target Information
C11orf84 negatively regulates the transcriptional activator activity of SPIN1 by inhibiting its histone methyl-binding ability. It represses SPIN1-regulated gene expression and Wnt signaling pathway activation. Also inhibits histone methyl-binding of SPIN2A, SPIN2B, SPIN3, and SPIN4.
(Source: UniProt, PubMed:29061846)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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