Thermo Fisher Scientific ACMSD Polyclonal Antibody
Thermo Fisher Scientific의 ACMSD Polyclonal Antibody는 인간 유래 단백질을 인식하는 토끼 IgG 항체로, Western blot에 적합합니다. 합성 펩타이드로부터 제작되었으며, 고순도의 액상 형태로 제공됩니다. 신경퇴행성 질환 연구용으로 활용 가능합니다.
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human ACMSD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606418 |
Product Specific Information
Peptide sequence:
NPMNPKKYLG SFYTDALVHD PLSLKLLTDV IGKDKVILGT DYPFPLGELE
Sequence homology:
Cow: 100%; Dog: 100%; Guinea Pig: 85%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 93%; Zebrafish: 93%
Target Information
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
[Supplied by OMIM, Oct 2004]
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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