Thermo Fisher Scientific B7-H6/NCR3LG1 (Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1) Monoclonal Antibody (B7H6/4821)
인간 B7-H6/NCR3LG1 단백질을 인식하는 Mouse IgG1 단클론 항체. IHC(P) 및 IHC(PFA) 적용 가능. Protein A/G 정제, PBS(pH 7.4) 용액 형태, 보존제 없음. 종양세포 표면 B7-H6와 NKp30 결합 연구용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | B7H6/4821 |
| Immunogen | Recombinant fragment (around aa38–169) of human NCR3LG protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
B7-H6 (NCR3LG1) is a transmembrane endogenous ligand expressed on the surfaces of tumor cells.
B7-H6 binds with NKp30 present on NK cells, leading to NK cell activation and target cell cytolysis.
It is not constitutively expressed on normal tissue, though its expression under certain conditions is under investigation.
B7-H6 has been detected on circulating pro-inflammatory CD14(+)CD16(+) monocytes in some patients with sepsis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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