Thermo Fisher Scientific FBXW2 Polyclonal Antibody
Human FBXW2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific FBXW2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FBXW2 (Recombinant protein control fragment: Product #RP-103661) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641561 |
Product Specific Information
Immunogen sequence:
LYIMDLRTES LISRWPLPEY RKSKRGSSFL AGEASWLNGL DGHNDTGLVF ATSMPDHSIH LVLWKEHG
Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 100%
Target Information
F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins are critical for the ubiquitin-mediated degradation of cellular regulatory proteins. F-box proteins are one of the four subunits of ubiquitin protein ligases (SCFs), which bring ubiquitin conjugating enzymes to substrates recruited by specific F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of WD-40 repeats, leucine-rich repeats, or other protein-protein interaction domains.
This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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