Thermo Fisher Scientific GPR132 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

3-28 µg/mL

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 18 amino acid peptide from 3rd extracellular domain of human GPCR G2A

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2113512

Product Specific Information

PA1-32755 detects GPCR G2A from human samples.

Target Information

GPCR G2A is a G-protein linked receptor for lysophosphatidylcholine (LPC). It may play a role as a sensor of LPC levels at sites of inflammation to limit tissue-infiltrating-cells and progression to overt autoimmune disease and functions at the G2/M checkpoint to delay mitosis. It also may serve as a mechanism for T and B cells, and other cell types, to slow their proliferation and repair damaged DNA. It is highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus, but weakly expressed in heart and lung. In atherosclerotic plaques, expression was observed around the lipid core and at the shoulder region. It is induced by DNA-damaging agents.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.