Thermo Fisher Scientific TIMP2 Monoclonal Antibody (OTI1C4), TrueMAB
인간 TIMP2 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 적합. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공. PBS 기반 저장용액, 보존제 없음. 세포외 기질 단백질 연구 및 MMP 관련 연구에 활용 가능.
- 판매단위
- pk
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Thermo Fisher Scientific TIMP2 Monoclonal Antibody (OTI1C4), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C4 |
| Immunogen | Full length human recombinant protein of human TIMP2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TIMP-1 and TIMP-2 are inhibitors of the matrix metalloproteinase family, playing a crucial role in maintaining connective tissue integrity.
TIMP-2 binds strongly to both latent and active forms of 72 kDa Type IV collagenase (MMP-2, gelatinase A) and also to active 92 kDa Type IV collagenase (MMP-9, gelatinase B).
It inhibits proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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