Thermo Fisher Scientific ZBTB4 Polyclonal Antibody
인간 ZBTB4 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(glycerol 포함) 용액 형태로 제공. ZBTB4의 메틸화 DNA 결합 및 전사 억제 연구에 적합.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZBTB4. Recombinant protein control fragment (Product # RP-103705) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649772 |
Product Specific Information
Immunogen sequence:
TPTPVIAYSK GSAGTRPGDV KEEAPQEMQV SSSSGEAGGG STAAEEASET ASLQDPIISG GEEPPVVASG GSYVYPPV
Highest antigen sequence identity to the following orthologs:
- Mouse: 88%
- Rat: 86%
Target Information
The ZBTB family of proteins comprises diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. Similar to Kaiso, a zinc-finger protein that binds methylated CpGs, ZBTB4 can bind methylated DNA and repress transcription. ZBTB4 associates with the Sin3/histone deacetylase co-repressor and represses expression of P21CIP1 as part of a heterodimeric complex with Miz1. In cultured cells, depletion of ZBTB4 promotes cell cycle arrest in response to p53 activation and suppresses apoptosis through regulation of P21CIP1, suggesting ZBTB4 is a critical determinant of the cellular response to p53 activation. HIPK2, a kinase involved in cellular proliferation and survival, phosphorylates and down-regulates ZBTB4 under normal growth conditions; this degradation increases with DNA damage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific GYG2 Polyclonal Antibody
799,600원
Thermo Fisher Scientific
Thermo Fisher Scientific PCSK1N Polyclonal Antibody
796,700원
Thermo Fisher Scientific
Thermo Fisher Scientific ZBTB4 Polyclonal Antibody
773,300원
Thermo Fisher Scientific
Thermo Fisher Scientific DPM2 Polyclonal Antibody
773,300원
Thermo Fisher Scientific
Thermo Fisher Scientific SOWAHA Polyclonal Antibody
773,300원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|