Thermo Fisher Scientific Proteasome 19S S3 Polyclonal Antibody
Western blot 및 IHC(P)에서 사용 가능한 Proteasome 19S S3 폴리클로날 항체. Rabbit IgG로 제작되었으며 Human, Mouse, Rat에 반응. Protein A로 정제된 액상 형태로 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Proteasome 19S 10B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.
The 20S core consists of four rings of 28 non-identical subunits—two rings of seven alpha subunits and two rings of seven beta subunits.
The 19S regulator includes a base (six ATPase subunits and two non-ATPase subunits) and a lid (up to ten non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
A modified form, the immunoproteasome, plays a critical role in processing class I MHC peptides.
This gene encodes one of the non-ATPase subunits of the 19S regulator lid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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