Thermo Scientific™

LanthaScreen™ Tb-PY20 Antibody Kit

A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological자세히 알아보기

A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate.

For use in combination with Fluorescein-poly-GT (Cat. No. PV3610) or Fluorescein-poly-GAT (PV3611) to evaluate inhibitors in medium to high throughput screening applications.

사양

항원Tyrosine kinases

농도0.45 mg/mL

콘주게이트Tb (Terbium)/FITC/Lanthanide Chelates

항원의 분자량150 kDa

수량25 μg

인허가 상태RUO

연구 영역Kinase Antibodies and Immunoassays

일차 또는 이차Primary

포장1 Kit

항체 분자량150,000 Da

어세이 입력Biochemical terbium phospho-specific activity

형식384-well Plate

여기/방출340/490, 520 nm

배송 조건Dry Ice

판독End Point

연구 카테고리Signal Transduction

타겟 입력ABL1 G250E, CSF1R, CSK, EPHA5, KIT, PDGFRA T674I, PDGFRA V561D, PTK6, RET Y791F, SYK, TYRO3, ZAP70, FGFR1, FGFR2, BLK, EGFR, EPHB2, FGFR4, IGF1R, LYNA, MATK, MERTK, NTRK3, RET V804L, ROS1, TEK, TTK, FLT1, MUSK, SRCN1, TEC, ABL1 E255K, BMX, EPHA4, FYN, PTK2, PTK2B, RET, ABL1 T315I, EPHA3, EPHB4, FLT3, FLT4, INSR, LCK, YES1, EGFR L858R, ERBB4, KDR, MET, TNK2, ABL1, ABL2, AXL, FGFR3, FGFR3 K650E, FGR, HCK, KIT V654A, EPHA1, EPHA8, EPHB3, INSRR, LYNB, MST1R, NTRK1, PDGFRA D842V, SRMS, EGFR L861Q, EPHA2, FER, LTK, PDGFRA, PDGFRB, EGFR T790M, EPHA7, EPHB1, MET M1250T, FRK, ITK, FLT3 D835Y, SRC, ABL1 Y253F, BTK, DDR2, FES, KIT T670I, TXK, ERBB2, NTRK2

타겟 효소Tyrosine Kinases

기술TR-FRET

검증된 키나아제ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70

제품라인LanthaScreen™

Unit SizeEach