Thermo Fisher Scientific eIF4G3 Polyclonal Antibody
Human eIF4G3 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:500~1:1,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보존. 단백질 번역 및 세포 증식 조절 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human eIF4G3. Recombinant protein control fragment (Product #RP-94019) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640975 |
Product Specific Information
Immunogen sequence:
TEEIMSGGGS RNPTPPIGRP TSTPTPPQQL PSQVPEHSPV VYGTVESAHL AASTPVTAAS DQKQEEKPKP DPVLKSPSPV LRLVLSGEKK EQEGQTSETT AIVS
Highest antigen sequence identity to orthologs:
- Mouse: 89%
- Rat: 89%
Target Information
The protein encoded by this gene is part of the eIF4F complex, which mediates mRNA cap recognition and transport to the ribosome.
A microRNA (miR-520c-3p) negatively regulates synthesis of this protein, leading to decreased global protein translation and cell proliferation.
This protein is therefore a key component of the anti-tumor activity of miR-520c-3p.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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