Thermo Fisher Scientific Human LIMK1, His Tag Recombinant Protein

Thermo Fisher Scientific Human LIMK1, His Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution

• Assay-dependent

Product Specifications

Product Specific Information

• For maximum recovery, spin prior to use.
• Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use material directly from original packaging.
• For larger sizes, reduce freeze/thaw cycles by preparing aliquots (do not prepare aliquots below 20 µL).
• Do not store kinase diluted.
• Properly stored at -80°C, product guaranteed for 6 months from date of purchase.
• Protein Form: Catalytic

Target Information

LIMK1 is a serine/threonine kinase involved in regulation of actin cytoskeletal changes via phosphorylation of cofilin. LIMK1 also plays a role in brain development. LIM domains are highly conserved cysteine-rich structures containing two zinc fingers, typically mediating protein-protein interactions. LIMK1 and LIMK2 form a subfamily with two N-terminal LIM motifs and a C-terminal kinase domain. LIMK1 may participate in intracellular signaling pathways and is associated with cognitive impairment in Williams syndrome due to hemizygosity.

Usage Note

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.