Thermo Fisher Scientific H1FOO Polyclonal Antibody
H1FOO 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 최적화됨. 인간 시료에 반응하며 Rabbit IgG 형식으로 제작됨. 단백질 A 및 항원 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능.
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Thermo Fisher Scientific H1FOO Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Publications: - [References not available]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 138–167 amino acids from the central region of human H1FOO |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2900887 |
Target Information
Eukaryotic histones are basic and water-soluble nuclear proteins forming hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn to create chromosomal fibers. Two molecules of each core histone (H2A, H2B, H3, and H4) form an octamer consisting of two H2A-H2B dimers and two H3-H4 dimers that are nearly symmetrical in tertiary structure.
Over 80% of nucleosomes contain the linker histone H1, derived from an intronless gene, which interacts with linker DNA between nucleosomes and mediates compaction into higher-order chromatin.
H1FOO (H1 histone family, member O, oocyte-specific), also known as OSH1, is a 346 amino acid oocyte-specific histone localized to both the nucleus and cytoplasm. It is expressed as multiple alternatively spliced isoforms and plays an important role in gene control during oogenesis and early embryogenesis, crucial for meiotic maturation of germinal vesicle-stage oocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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