Thermo Fisher Scientific GPIHBP1 Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GPIHBP1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPIHBP1,uniProtId:Q8IV16-1,ncbiNodeId:9606,antigenRange:65-150,antigenLength:184,antigenImageFileName:PA5-64273_GPIHBP1_Q8IV16-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64273_GPIHBP1_Q8IV16-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642142

Product Specific Information

Immunogen sequence: CYTCKSLPRD ERCNLTQNCS HGQTCTTLIA HGNTESGLLT THSTWCTDSC QPITKTVEGT QVTMTCCQSS LCNVPPWQSS RVQDPT

Highest antigen sequence identity to the following orthologs: Mouse - 59%, Rat - 57%.

Target Information

GPI-anchored HDL-binding protein 1 (Gpihbp1) is a novel protein that may be involved in the regulation of the delivery of fats to cells for energy and storage. Digested fats travel to the small intestine, where they are packaged into chylomicrons (particles filled with triglycerides). Chylomicrons then travel through the bloodstream and deliver triglycerides to tissues that are hungry for fuel or to adipose tissue for energy storage. Triglycerides are broken down or hydrolyzed by the enzyme lipoprotein lipase (LpL). The triglyceride breakdown products are then taken up and used by cells. Gpihbp1 is the molecule in capillaries that facilitates the capture of chylomicrons and facilitates the interaction with LpL. It has been shown that fats in the bloodstream are not readily metabolized in the absence of GPIHBP1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.