Thermo Fisher Scientific SPANXB1 Polyclonal Antibody
Thermo Fisher Scientific의 SPANXB1 Polyclonal Antibody는 인간 SPANXB1 단백질을 인식하는 토끼 IgG 항체로, IHC, ICC/IF, ELISA 등에 적합합니다. 고순도 Protein A 정제, 1 mg/mL 농도, 안정적인 액상 형태로 제공되며 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human SPANXB1 (amino acids 1–80) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Temporally regulated transcription and translation of several testis-specific genes are required to initiate the molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa.
This gene is a member of the SPANX family of cancer/testis-associated genes located in a cluster on chromosome X.
SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments.
SPANXB1 maps to chromosome X in a head-to-tail orientation with SPANX family member B2, which appears to be a duplication of the B1 locus.
SPANXB genes are unique members of this family, containing an additional 18 nucleotides in their coding region compared to most family members.
Although the encoded protein includes consensus nuclear localization signals, its major localization site is in the cytoplasmic droplets of ejaculated spermatozoa.
This protein serves as a biochemical marker for studying unique spermatozoa structures and may help define its role in spermatogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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