Thermo Fisher Scientific EXO5 Polyclonal Antibody
Thermo Fisher Scientific EXO5 Polyclonal Antibody는 인간 EXO5 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot과 Immunocytochemistry에 적합하며, DNA 복구 연구용으로 사용됩니다. 항원 친화 크로마토그래피로 정제된 액상 제품으로 안정적인 장기 보관이 가능합니다.
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- PA5110957
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- pk
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Thermo Fisher Scientific EXO5 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human EXO5. Recombinant protein control fragment (Product #RP-94441). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856368 |
Product Specific Information
Immunogen sequence:
ELPGFLAPEK AAVLDTGASI HLARELELHD LVTVPVTTKE DAWAIKFLNI LLLIPTLQSE GHIREFPVFG EVEGVLLVGV IDELHYTAKG
Target Information
Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair.
Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (ICLs) damage.
Has both 5–3 and 3–5 exonuclease activities with a strong preference for 5-ends.
Acts as a sliding exonuclease that loads at ssDNA ends and then slides along the ssDNA prior to cutting.
The sliding and 3–5exonuclease activities are abolished upon binding to the replication protein A (RPA) complex that enforces 5-directionality activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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