Thermo Fisher Scientific Phospho-Parathyroid Hormone Receptor 1 (Ser493, Ser495) Polyclonal Antibody
인체 PTH1 수용체의 Ser493/Ser495 인산화 부위를 인식하는 폴리클로날 항체입니다. Western blot에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 농도의 액상 형태로 제공되며, 4°C 단기 또는 -20°C 장기 보관이 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human PTH1 around the phosphorylation site of Ser493/Ser495 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Parathyroid hormone receptor 1 (PTH1R) is a member of the G-protein coupled receptor family. It serves as a receptor for parathyroid hormone (PTH) and parathyroid hormone-like hormone (PTHLH). Its activity is mediated by G proteins activating adenylyl cyclase and a phosphatidylinositol-calcium second messenger system. Mutations in this receptor are associated with Jansen’s metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), and enchondromatosis. PTH1R expression has been reported in bone, breast, brain, colon, GI tract, kidney, liver, placenta, skin, umbilical cord, and uterus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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