Thermo Fisher Scientific SMUBP2 Polyclonal Antibody
SMUBP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. 고순도 Protein A 정제, -20°C 보관 안정성.
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Thermo Fisher Scientific SMUBP2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human SMUBP2, amino acids 271–355 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SMUBP2 is a 5′ to 3′ helicase that unwinds RNA and DNA duplexes in an ATP-dependent manner. It acts as a transcription regulator and is required for the transcriptional activation of the flounder liver-type antifreeze protein gene. It binds specifically to enhancer element B of the flounder antifreeze protein gene intron and to the insulin II gene RIPE3B enhancer region. SMUBP2 may also be involved in translation and binds to 5′-phosphorylated single-stranded guanine-rich sequences related to the immunoglobulin mu chain switch region, preferentially recognizing the 5′-GGGCT-3′ motif. It interacts with tRNA-Tyr and stimulates transcription of the human neurotropic virus JCV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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